Bioactive glass is a material class that is of potential interest for the application in endodontic therapy. Very recent research indicates that it is effective in vitro as an intracanal disinfectant; however, the mode of action is currently unknown.
In collaboration with investigators at the University of Zurich, we plan a review of the literature and the design of experiments that will help to understand the effectiveness of bioactive glass. Using E. faecalis, we will determine whether pH elevation alone or other processes are responsible for the antimicrobial effects. The next step in this research is to develop a model, based on our experience with experiments looking into disinfection solutions.
Dr. Christine Peters, email@example.com, 415.351.7120