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Faculty-Sponsored Research Areas 2008

Below is a list of Faculty with active research programs at the School. Interested students may contact the individual Faculty members, or the Student Research Coordinator Dr. Nejat Düzgünes. 

Tamer Alpagot (Department of Periodontics)

  • Molecular risk factors for periodontitis in HIV+ patients, including transforming growth factor and matrix metalloproteinases
  • Immune response by macrophages to Porphyromonas gingivalis infection

Leigh Anderson (Department of Anatomy)

  • Influence of sex hormones on endothelial cell function
  • Microvascular disease in diabetes
  • Salivary gland function in diabetes

Shelly Baumrind (Department of Orthodontics)

  • Evaluation of Orthodontic Treatment Outcomes
  • Internet-Shared Craniofacial Records Base Construction
  • Cross-cultural Studies of Facial Attractiveness
  • Clinical Analysis of 3D-CBCT images in Orthodontics
  • Mixed-Dentition Treatment Evaluation
  • RCT of Anchorage Loss in Orthodontic Treatment

David Chambers (Department Of Dental Practice)

  • Competency based education and evaluation
  • Data mining from clinical charts
  • Relationship between technique and operator variability
  • Practitioner decision making and response to advertising claims
  • Help with any statistical or research design question

Joel Cohen (Department of Physiology)

  • Electrophoretic mobilities of polymer-coated liposomes
  • Theory of polymer osmotic pressures; application to biocompatibility of surfaces and to protein and nucleic acid permeation through channels in biological membranes

James Dower (Department of Restorative Dentistry)

  • Ergonomics for visibility, productivity and health
  • Paresthesias from local anesthetics
  • Mandibular block injections and the anatomy of the temporomandibular space

 
Nejat Düzgünes (Department of Microbiology)

  • Therapy of HIV/AIDS: Lectin- and antibody-mediated targeting of cytotoxic nanoparticles to HIV-envelope expressing cells
  • Gene therapy of oral cancer: Selective gene delivery to oral cancer cells
  • Interaction of periodontal pathogens with oral epithelial cells and macrophages
  • Inhibition of prolonged bitter taste: Inhibition of bitter tastant uptake into oral epithelial cells

Stefan Highsmith (Department of Biochemistry)

  • Binding of Streptococcus mutans to hydroxyapatite
  • Mercury toxicity

Krystyna Konopka (Department of Microbiology)

  • Cancer cell-specific gene expression for gene therapy of oral cancer
  • The effect of serum on the size and charge of lipid-DNA complexes used for gene delivery
  • Survivin promoter-driven gene expression in cancer and non-cancer cells
  • Inhibitory effect of lysozyme, histatins and antifungals on Candida biofilms
  • Photodynamic antimicrobial chemotherapy (PACT) of Candida biofilms

Anders Nattestad(Department of Oral and Maxillofacial Surgery)

  • Treatment of alveolar ostitis (dry socket)
  • Local anesthesia efficacy and pain during injection using different techniques
  • Dental students surgical extraction experience and perception of self-assessed competence
  • Models to teach surgical skills
  • Cone Beam Computer Tomography (CBCT) in 3rd molar surgery training
  • Bisphosphonates and Oral and Maxillofacial Surgery

Ove Peters (Department of Endodontics)

  • Canal preparation with NiTi rotary instruments
  • 3D reconstruction from CT data
  • Disinfection efficacy of irrigation solutions
  • Periapical healing and endogenous anti-inflammatory pathways
  • Antibacterial mechanism of bioactive glass
  • Physical properties of NiTi rotary instruments

Karen Schulze (Department of Restorative Dentistry)

  • Dentin and Enamel Bonding
  • Shear bond tests between different materials
  • Fracture mechanics on zirconia post and cores
  • Clinical studies on A.R.T.(Atraumatic Restorative Treatment) in developing countries

Mirek Tolar (Department of Orthodontics)

  • Cultivation conditions enhancing multiplication of human adult mesenchymal stem cells for applications in dentistry
  • Cultivation conditions enhancing osteogenic differentiation of human adult mesenchymal stem cells for applications in dentistry
  • Effect of autologous human platelet-rich plasma on multiplication and differentiation of human adult mesenchymal stem cells in vitro
  • Effect of growth factors on multiplication and differentiation of human adult mesenchymal stem cells in vitro

Marie Tolarova (Department of Orthodontics)

  • Causes and prevention of cleft lip and palate anomalies
  • Candidate genes involved in etiology of craniofacial anomalies
  • Polymorphisms of MTHFR, RFC1, MSX1, and TGFB3 genes
  • Association of maternal nutrition with cleft lip and palate
  • Use of saliva for molecular genetic studies
  • Heredity and missing teeth
  • Maxillary midline diastema and genetics

Douglas A. Young (Department of Dental Practice)

  • Caries management by risk assessment
  • Minimally invasive dentistry
  • Lasers in dentistry
  • Caries detection
  • Caries prevention
  • New treatment modalities
  • Product testing
  • New methods of student learning, teaching, and assessment