DMD, University of Kiel, Germany 1990
PhD, University of Zurich, Switzerland, 2001
MS, University of California San Francisco, CA, 2003
Cert. endodontics, University of California San Francisco, CA, 2006
Dr. Peters joined the Dugoni School of Dentistry in 2007. Previously he held faculty positions at the University of Heidelberg, Germany, the University of Zurich, Switzerland and the University of California San Francisco. His clinical background is in endodontics, he was board certified in 2010. Dr. Peters has a sustained publication record spanning more than 25 years and has successfully applied for extramural funding; he serves as an editor and reviewer for several journals in endodontics and dental research. His main scientific interests are the design and performance of root canal instruments. In this area Dr. Peters has developed novel methods of three-dimensional imaging and mechanical testing. He has also assessed the efficacy of antimicrobial regimes in root canal treatment. More recently he became involved in research in endodontic and stem cell biology.
Dr. Peters' expertise and research interests are two core lines of research: testing and design of root canal instrumentation / disinfection techniques and secondly aspects of the host response during pulpal and periapical inflammation.
Using special equipment such as a unique torque-testing machine and proprietary software for micro-computed tomography, Dr. Peters' lab test nickel-titanium rotary instruments, simulating clinical procedures. Usage parameters such as particular hand movements, rotational speed and instrument sequence are of great interest for clinicians and are evaluated with respect to instrument breakage and the quality of the resulting canal preparation. Standard techniques such as bacterial culturing and fluorescent staining allow us to estimate the efficacy of root canal disinfection strategies in vitro, with particular reference to bacterial biofilms.
Stem cells of the apical papilla (SCAP) are the main target of biologic research in Dr. Peters' lab. Of interest is the response of these cells to environmental and exogenous cues, such as LPS and immunomodulatory substances. To this end, we utilize standard methods such as immunofluorescence, but also contemporary molecular biological techniques such as PCR, flow cytometry and multiplex protein assays.